Aging is the result of tissue energy alteration, therefore when an external energy source is applied, such as radiofrequency (RF), high-intensity focused ultrasound (HIFU), and/or their combination, it results in their renewal and improvement of skin aging. Nowadays, even for the most difficult parts such as the neck and décolleté, these modern non-invasive aesthetic technologies are applied with results from one treatment. The combination protocols will offer maximum results, if they are used under the right conditions.